Re-awaken
Your Skin
From within

RADIESSE^® is a regenerative biostimulator that promotes healthy-looking skin*
It works by stimulating the natural regenerative processes that activate production of collagen, elastin, and other key skin components.
This leads to improved skin quality—boosting skin firmness, elasticity, and hydration, helping to reverse visible the signs of aging.^1-8,11

See Before and After

*“Healthy-looking skin” is defined by regeneration of Collagen I and III, elastin, proteoglycans, and angiogenesis.
Actual RADIESSE^® patient. Individual results may vary.

Radiant Skin BEGINS Today

Immediate lift and definition^4,9,10

Improved skin quality, firmness, elasticity, and hydration^3-5,11

Results lasting up to 2 years in some individuals^7,8,10

Your Skin Changes Over Time

That’s probably no surprise—but do you know exactly how? Two important components are collagen and elastin, which help keep facial lines and wrinkles at bay. Unfortunately, aging and environmental factors (think sun damage) make it harder for your body to produce collagen and elastin. This can cause facial skin to wrinkle and sag, stealing from your youthful appearance.^1,7,8

picture of two smooth and wrinkle-free hands showing the results of Radiesse — Actual patient. Individual results may vary.

Immediate and Long-Term Results

RADIESSE^® instantly smooths wrinkles and folds and provides long-term benefits from the stimulation of new collagen and elastin.^5,6,11,12

Experience RADIESSE^®

Award Winning

Best Biostimulatory filler for Facial Volume

Favorite Filler for Hand Rejuvenation

Best Filler for Hand Rejuvenation

Have more questions?

Check out these common questions for more info about RADIESSE^® and what you can expect from treatment.

Ready for a consultation?

Find a provider in your area and schedule a visit to see if RADIESSE^® is right for you.

RADIESSE^® and RADIESSE^® (+) are indicated for subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, and for the rejuvenation of the hand. RADIESSE^® injectable implant diluted 1:2 with 0.9% sterile saline for injections is intended for the treatment of moderate to severe décolleté wrinkles. After injection, patients may experience redness, bruising, swelling or other local side effects. Most side effects of treatment resolve within a few days. More rare side effects may include swelling that lasts longer, unevenness or firmness in the area injected, and as with any injection, there may be a risk of infection. Be sure to inform your healthcare professional of any known allergies, especially to sodium hyaluronate and lidocaine hydrochloride (for lidocaine versions) or to amide-type local anesthetics before treatment. This product may not be right for you. Talk to your aesthetic healthcare professional. Please see Instructions for Use for full list of warnings and precautions. The Instructions for Use are available here.

RADIESSE® Instructions for Use. Merz North America, Inc. July 2025.
RADIESSE® (+) Instructions for Use. Merz North America, Inc. April 2023.
Aguilera SB, et al. Aesthet Surg J. 2023;43(10):1063-1090.
McCarthy AD, et al. Plast Reconstr Surg Glob Open. 2024;12(8):e6068.
Yutskovskaya YA, Kogan EA. J Drugs Dermatol. 2017;16(1):68-74.
Nowag B, et al. Presented at: AMWC 2019; Monte Carlo, Monaco; April 2–4, 2019.
Fabi SG, Alhaddad M, Boen M, Goldman M. J Drugs Dermatol. 2021;20(5):534-537.
Bass LS, Smith S, Busso M, McClaren M. Aesthet Surg J. 2010;30(2):235-238.
Tzikas TL. Dermatol Surg. 2008;34(Suppl 1):S9-S15.
van Loghem JV, Yutskovskaya YA, Philip Werschler W. J Clin Aesthet Dermatol. 2015;8(1):38-49.
González N, Goldberg DJ. Dermatol Surg. 2019;45(4):547-551.
Yutskovskaya Y, et al. J Drugs Dermatol. 2014;13(9):1047-1052.
Baumann L. J Pathol. 2007;211(2):241-251.
Durkin A, et al. J Cosmet Dermatol. 2021;20:442-450.

Re-awaken Your Skin From within