About Radiesse - Merz Aesthetics Canada

Actual patient. Individual results may vary.

Radiesse^®

RADIESSE^® and RADIESSE^® (+) are indicated for subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, and for the rejuvenation of the hand. RADIESSE^® injectable implant diluted 1:2 with 0.9% sterile saline for injections is intended for the treatment of moderate and severe décolleté wrinkles.^1,2

Unique calcium hydroxylapatite (CaHA) gel formulations of RADIESSE^®provide a matrix for immediate lift and contour, and high density of collagen and elastin provides for observed long-term structural support.^2-6 

Skin revitalized from within with RADIESSE^®stays defined and sustained for up to 2 years in some individuals.^4,11,13

RADIESSE^® for facial wrinkles and folds

RADIESSE^® provides foundational treatment to address the most in-demand age-related aesthetic concerns for the lower face.

Provides immediate lift and definition by restoring lost volume in areas of the lower face^4,5
Regenerates collagen and elastin^6,8

Photo of lower half of woman's face. — Actual patient. Individual results may vary.

RADIESSE^® for Décolleté

RADIESSE^® smooths moderate and severe décolleté wrinkles¹

Provides regeneration, skin-tightening, and helps to improve skin quality^6-10*

*“Skin quality” is defined by regeneration of Collagen I and III, elastin, proteoglycans, and angiogenesis.^6-10 

beforeafter

Radiesse décolleté
chest before and after — Actual patient. Individual results may vary.

RADIESSE^® for Hands

RADIESSE^® is the only CaHA dermal filler proven to immediately restore volume loss in the back of the hands for smooth, natural-looking results.¹

Helps restore a more youthful appearance to hands¹
Reduces the appearance of tendons and veins²
Delivers smooth, natural-looking results that last up to a year in most patients²

beforeafter

Before and after comparison of Radiesse treatment for hands. — Actual patient. Individual results may vary.

Become a provider

RADIESSE^® and RADIESSE^® (+) are indicated for subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, and for the rejuvenation of the hand. RADIESSE^® injectable implant diluted 1:2 with 0.9% sterile saline for injections is intended for the treatment of moderate and severe décolleté wrinkles.

Warnings:

As with all dermal fillers, introduction of RADIESSE^® or RADIESSE^® (+) injectable implant into the vasculature may lead to embolization, occlusion of the vessels, ischemia, or infarction.
Rare but serious adverse events associated with the intravascular injection of soft tissue fillers in the face have been reported and include temporary or permanent vision impairment, blindness, cerebral ischemia or cerebral hemorrhage, leading to stroke, skin necrosis, and damage to underlying facial structures.
Immediately stop the injection if a patient exhibits any of the following symptoms, including changes in vision, signs of a stroke, blanching of the skin, or unusual pain during or shortly after the procedure.
Patients should receive prompt medical attention and possibly evaluation by an appropriate healthcare practitioner specialist should an intravascular injection occur.
Use of RADIESSE^® or RADIESSE^® (+) injectable implant in any person with active skin inflammation or infection in or near the treatment area should be deferred until the inflammatory or infectious process has been controlled.
Injection procedure reactions have been observed consisting mainly of short-term (i.e., <7 days) bruising, redness, swelling, lumpiness, pain, itching, discolouration, and tenderness.
Do not overcorrect (overfill) a contour deficiency because the depression should gradually improve within several weeks as the treatment effect of RADIESSE^® (+) injectable implant occurs. In extreme cases site rupture could occur with overcorrection.
Not intended for use in the breasts or for use in the lips.

Consult the Instructions for Use for a complete list of warnings, precautions, and other important safety information. The Instructions for Use are available by calling us at 1-866-815-8715 or found here.

RADIESSE Instructions for Use. Merz North America, Inc. July 2025.
RADIESSE (+) Instructions for Use. Merz North America, Inc. November 2016.
Tzikas TL, et al. Dermatol Surg. 2008;34(suppl 1):S9-S15.
Moers-Carpi MM, Tufet JO. Calcium hydroxylapatite versus nonanimal stabilized hyaluronic acid for the correction of nasolabial folds: a 12-month, multicenter, prospective, randomized, controlled, split-face trial. Dermatol Surg. 2008;34(2):210-215.
Berlin AL, Hussain M, Goldberg DJ. Calcium hydroxylapatite filler for facial rejuvenation: a histologic and immunohistochemical analysis. Dermatol Surg. 2008;34(suppl 1):S64-S67.
Yutskovskaya YA, et al. J Drugs Dermatol. 2014;13(9):1047-1052.
González N, Goldberg D. J. Dermatol Surg. 2019;45(4):547-551.
Yutskovskaya YA, et al. J Drugs Dermatol. 2017;16(1):68-74.
Nowag B, et al. Presented at: AMWC 2019; Monte Carlo, Monaco; April 2-4, 2019.
Yutskovskaya YA, et al. J Drugs Dermatol. 2020;19(4):405-411.
Fabi SG, Alhaddad M, Boen M, Goldman M. J Drugs Dermatol. 2021;20(5):534-537.
van Loghem J, et al. J Clin Aesthet Dermatol. 2015;(8):38-49.
Bass LS, Smith S, Busso M, McClaren M. Aesthet Surg J. 2010;30(2):235-238.
McCarthy AD, et al. Plast Reconstr Surg Glob Open. 2024;12(8):e6068.
Lorenc ZP, et al. Aesthet Surg J. 2022;42(1):NP29-NP37.

Radiesse®

RADIESSE® for facial wrinkles and folds

RADIESSE® for Décolleté

RADIESSE® for Hands

Become a provider

Radiesse^®

RADIESSE^® for facial wrinkles and folds

RADIESSE^® for Décolleté

RADIESSE^® for Hands